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The product is used to detect the antigen of Influenza/ Covid-19 by qualitative detection of human saliva, nasopharyngeal swabs and oropharyngeal swabs.

The laboratory diagnosis method is virus isolation and culture, and the cell culture identification cycle is about 14 hours, which seriously affects the guidance of timely medication for patients in clinical practice, which is limited in clinical application. Compared with cell culture, reverse transcription polymerase chain reaction(RT-PCR) has higher sensivity, but the cost of RT-PCR is higher, the experimental time needs 4-6 hours, and it is highly  professional in laboratory operation, so its filed application is limited. The product used latex chromatogram is suitable for the diagnosis of influenza A, influenza B , Covid-19.

The test kits used the latex immunochromatography technology.

Influenza A/B:

  On the nitrocellulose membrane, McAb2 against influenza A virus and McAb 2 against influenza B were coated on the detection line(T2) and (T1) respectively, Goat anti mouse IgG was coated on the position of quality control line(C), and the mouse influenza virus A/B monoclonal antibody 1 labeled with red latex microspheres was fixed on the latex binding pad. When the positive samples of influenza B virus were detected, the antigen of influenza B virus in the samples could bind with the monoclonal antibody 1 against influenza B virus labeled with red latex on the latex binding pad to form a sandwich complex and move along the membrane under the action of chromatography. When passing through the detection line (T1),  it binds to the pre coated mcab-2 of influenza B virus and agglomerates to form a red band ;When the positive samples of influenza A virus were detected, the antigen of influenza A virus in the samples could bind with the monoclonal antibody 1 against influenza A virus labeled with red latex on the latex binding pad to form a sandwich complex and move along the membrane under the action of chromatography. When passing through the detection line (T2),  it binds to the pre coated mcab-2 of influenza A virus and agglomerates to form a red band. it combines with Goat anti mouse IgG to form a red band in quality control line (C); when testing negative samples, the negative samples only show red at the quality control line (c).

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